Pemeran Lex Luthor dalam film Batman v Superman: Dawn of Justice, Jesse Eisenberg menyatakan bahwa ia tertarik untuk mengerjakan sekuel dari film Zombieland. Ketika diwawancarai oleh Entertainment Weekly, Eisenberg mengungkapkan keinginannya tersebut meskipun tak tahu kapan proyek Zombieland 2 akan digarap.
“Yeah, it’d be wonderful to do. I know they’ve been trying to do it for a while, and I know they’re trying to figure out exactly what will occur in it. But it’s a kind of movie that, as soon as it came out, seemed appropriate to generate a sequel. It takes place in this odd, created world and features an ensemble of interesting characters that it’d be curious to see more of. I would hope that it happens, and I’m sure everybody would be happy to do it if it happens and it’s good. It’s also a strangely beloved movie, so it’s a thing you have to get right. Some sequels you don’t have to get exactly right, but this is the kind of movie you have to get right because people like it for personal reasons, even though it’s a zombie comedy.”
Ketika Zombieland menghentak bioskop pada tahun 2009 lalu, nama Jesse Eisenberg langsung melambung tinggi di industri perfilman Hollwyood. Tak hanya Eisenberg, nama sang sutradara Ruben Fleischer dan dua penulis naskahnya yaitu Rhett Reese dan Paul Wernick pun juga ikut meroket. Film yang dibuat dengan anggaran $23 juta ini bisa dibilang sukses secara finansial karena berhasil meraup pendapatan hingga $102 juta dari penayangannya di seluruh dunia.
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